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Karen Sanguinet

Karen Sanguinet.

Associate Professor/Scientist

Department of Crop & Soil Sciences
ITB 3025
PO Box 646420
Pullman WA 99164-6420 USA
Phone 509-335-3662

Google Scholar page

Sanguinet Lab Members

Sanguinet Lab Photos


Ph.D.     University of California-Berkeley
Plant Biology, 2003

B.S.       University of Wisconsin-Madison
Horticulture with specialization in Vegetable Crops, 1998

B.S.        University of Wisconsin-Madison
Genetics with Honors, 1998


Curriculum Vitae

Research Experience

Assistant Professor, Iwate University, 2013-2014
Senior Research Fellow, University of Massachusetts-Amherst, 2009-2012
Marie Curie Postdoctoral Fellow, University of Lausanne, Switzerland, 2005-2009
Postdoctoral Researcher, Plant Gene Expression Center, Albany, CA, 2004-2005
Graduate Student Researcher, University of California-Berkeley, 1998-2003

Research Interest

Research themes in the Sanguinet lab focus on factors that modulate growth and development, particularly in response to the environment. We use physiological, developmental, genetic and genomics approaches to study plant root development and architecture in models such as Arabidopsis thaliana and Brachypodium distachyon as well as crops such as pennycress, wheat and rice. Through characterization and analysis of mutants and natural populations, we hope to gain insight into the quantitative and qualitative control of root development in addition to studying genome-wide responses to abiotic stresses such as cold and drought.


(f/k/a Osmont, Karen S)

Hickey, K., M. Wood, T. Sexton, Y. Sahin, T. Nazarov, J. Fisher, K.A. Sanguinet, A. Cousins, H. Kirchhoff, and A. Smertenko. Drought Tolerance Strategies and Autophagy in Resilient Wheat Genotypes. Cells. 2022; 11(11):1765.

Wei, W., L. Xu, H. Peng. et al. A fungal extracellular effector inactivates plant polygalacturonase-inhibiting protein. Nat Commun 13, 2213 (2022).

Opdahl, L.J., R.W. Lewis, L.A. Kalcsits, T.S. Sullivan, and K.A. Sanguinet. (2021) Plant uptake of lactate-bound metals: a sustainable alternative to metal chlorides. Biomolecules 11(8), 1085. DOI: 10.3390/biom11081085.

Taylor, S.E., C.I. Pearce, K.A. Sanguinet, H. Hu, W.B. Chrisler, Y-M Kim, Z. Wang, and M. Flury. 2020. Polystyrene nano- and microplastic accumulation at arabidopsis and wheat root cap cells, but no evidence for uptake into roots, Environmental Science: Nano.

Ghimire, B., S. Hulbert, C. Steber, K. Garland-Campbell, and K.A. Sanguinet. 2020. Characterization of root traits for improvement of spring wheat in the Pacific Northwest, Agronomy Journal, 112 (1): 228-240.

Ma, X., K.A. Sanguinet, and P. Jacoby. 2020. Direct root-zone irrigation outperforms surface drip irrigation for grape yield and crop water use efficiency. Agricultural Water Management, 231; 105993.

Smertenko, T., G. Turner, D. Fahy, R.A.T. Brew-Appiah, R. Alfero-Alco, J. de Almieda Engler, K.A. Sanguinet,  amd A. Smertenko. 2019. Brachypodium distachyon MAP20 functions in metaxylem pit development and contributes to drought recovery, New Phytologist, 1-15.

Cong, W., Y. Miao, L. Xu, Y. Zhang, C. Yuan, J. Wang, T. Zhuang, X. Lin, L. Jiang, N. Wang, J. Ma, K.A. Sanguinet, B. Liu, S. Rustgi, and X.0 Ou. 2019. Transgenerational memory of gene expression changes induced by heavy metal stress in rice (Oryza sativa L.). BMC Plant Biology, 19 (1), 282.

Ma, X., K.A. Sanguinet, and P. Jacoby. 2019. Performance of direct root-zone deficit irrigation on Vitis vinífera L. cv. ‘Cabernet Sauvignon’ production and root distribution in southcentral Washington, Agricultural Water Management, 221, 47-57.

Brew-Appiah, R.A.T., L.M. Peracchi, and K.A. Sanguinet. 2019. Never the two shall mix: Robust indel markers to ensure the fidelity of two pivotal and closely-related accessions of Brachypodium distachyon. Plants 8 (6), E153.

Zhang, Z., T. Fu, Z. Lui, X. Wang, H. Xun, G. Li, B. Ding, Y. Dong, X. Lin, K.A. Sanguinet, B. Liu, and Y. Wu. 2019. Extensive changes in gene expression and alternative splicing due to homeologous exchange in rice segmental allopolyploids, Theoretical and Applied Genetics, 132(8): 2295-2308.

Lehman, T., and K.A. Sanguinet. 2019. Auxin and cell wall crosstalk as revealed by the Arabidopsis thaliana cellulose synthase mutant radially swollen 1, Plant and Cell Physiology, 60(7): 1487-1503.

Clark, I., S.S. Jones, J.P. Reganold, K.A. Sanguinet, and K.M. Murphy. 2019. Agronomic performance of perennial grain genotypes in the Palouse region of the Pacific Northwest, USA, Frontiers in Sustainable Food Systems, 3, 39.

Brew-Appiah, R.A.T., and K.A. Sanguinet. 2018. Considerations of AOX functionality revealed by critical motifs and unique domains, International Journal of Molecular Sciences, 19(10), 2972

Brew-Appiah, R.A.T., Z.B. York, V. Krishnan, E.H. Roalson, and K.A. Sanguinet. 2018. Genome-wide identification and analysis of the ALTERNATIVE OXIDASE gene family in diploid and hexaploid wheat, PloS One 13 (8), e0201439

Handakumbura, P.P., K. Brow, I.P. Whitney, K. Zhao, K.A. Sanguinet, S.J. Lee, J. Olins, S.P. Romero-Gamboa, M.J. Harrington, C.J. Bascom, K.J-M. MacKinnon, M.T. Veling, L. Liu, J.E. Lee, J.P. Vogel, R.C. O’Malley, M. Bezanilla, L.E. Bartley, and S.P. Hazen. 2018. Brachypodium distachyon SWAM1 is a positive regulator of secondary cell wall synthesis and biofuel feedstock attributes and is not found in the Brassicaceae, The Plant Journal, 96 (3), 532-545

Wu, Y., Y. Sun, S. Sun, G. Li, J. Wang, B. Wang, X. Lin, M. Huang, Z. Gong, K.A. Sanguinet, Z. Zhang, and B. Liu. 2018. Aneuploidization under segmental allotetraploidy in rice and its phenotypic manifestation, Theoretical and Applied Genetics, 1-13

Martinez, S., A. Thompson, N. Wen, L. Murphey, K.A. Sanguinet, C. Steber, and K. Garland-Campbell. 2018. Registration of the Louise/Alpowa Wheat Recombinant Inbred Line Mapping Population, Journal of Plant Registrations 12(2): 282-287.

Liu, D., N. Zefroosh, K. Hines, W. Fang, K.A. Sanguinet, L. Goldner, and T.I. Baskin. 2017. Cellulose synthase motility during primary cell wall synthesis in the grass Brachypodium distachyon, Scientific Reports, 7 (1): 15111

Lehman, T., A. Smertenko, and K.A. Sanguinet. 2017. Auxin, microtubules, and vesicular trafficking: conspirators behind the cell wall. Journal of Experimental Botany 68(13): 3321-3329.

Sun, S., Y. Wu, X. Lin, J. Wang, J. Yu, Y. Sun, Y. Miao, Q. Li, K.A. Sanguinet, and B. Liu. 2017. Hybrid weakness in a rice interspecific hybrid is Nitrogen-dependent, and accompanied by changes in gene expression at both total transcript level and parental allele partiitioning. PloS One 12 (3), e0172919.

Itoh, J-I, Y. Sato, Y. Sato, K. Hibara, S. Shimizu-Sato, H. Kobayashi, H. Takehisa, K.A. Sanguinet, N. Namiki, and Y. Nagamura. 2016. Genome-wide analysis of spatiotemporal gene expression patterns during early embryogenesis in rice. Development, 143: 1217-1227

Handakumbura, P.P., D.A. Matos, K.S. Osmont, M.J. Harrington, K. Heo, K. Kafle, S.H. Kim, T.I. Baskin, and S.P. Hazen. 2013. Perturbation of Brachypodium distachyon CELLULOSE SYNTHASE A4 or 7 results in abnormal cell walls. BMC Plant Biology, 13: 131.

Sankar, M., K.S. Osmont, J. Rolcik, B. Gujas, D. Tarkowska, M. Strnad, I. Xenarios, and C.S. Hardtke. 2011. A qualitative continuous model of cellular auxin and brassinosteroid signaling and their crosstalk. Bioinformatics, 27(10): 1404-1412.

Jun, J.H., E. Fiume, A. Roeder, L. Meng, V.K. Sharma, K.S Osmont, C. Baker, C.M. Ha, E.M. Meyerowitz, L.J. Feldman, and J.C. Fletcher. 2010. Comprehensive analysis of CLE gene expression and over-expression activity in Arabidopsis. Plant Physiology, 154: 1721-1736.

Scacchi, E.*, K.S. Osmont*, J. Beuchat, P. Salinas, M. Navarrete-Gómez, M. Trigueros, C. Ferrándiz, and C.S. Hardtke. 2009. Dynamic, auxin-responsive plasma membrane to nucleus movement of Arabidopsis BRX. Development, Vol. 136: pp. 2059-2067. *-equal contributions

Rodrigues, A., J. Santiago, S. Rubio, A. Saez, K.S. Osmont, J. Gadea, C.S. Hardtke, P.L. Rodriguez. 2009. The Short-Rooted Phenotype of the brevis radix Mutant Partly Reflects Root Abscisic Acid Hypersensitivity. Plant Physiology, 149: 1917-28.

Osmont, K.S. and C.S. Hardtke. 2008. The topless plant developmental phenotype explained! Genome Biology, 9:219.

Hardtke, C.S., E. Dorcey, K.S. Osmont, and R. Sibout. 2007. Phytohormone collaboration: zooming in on auxin-brassinosteroid interactions. Trends in Cell Biology, Vol. 17: pp. 485-492.

Osmont, K.S., R. Sibout, and C.S. Hardtke. 2007. Hidden Branches: Developments in Root System Architecture. Annual Review of Plant Biology, Vol. 58: pp. 93-113.

Mouchel, C.F., K.S. Osmont, and C.S. Hardtke. 2006. BRX mediates feedback between brassinosteroid levels and auxin signalling in root growth. Nature, Vol. 443: pp. 458-461.

Briggs, G.C., K.S. Osmont, C. Shindo, R. Sibout, and C.S. Hardtke. 2006. Unequal genetic redundancies in Arabidopsis – a neglected phenomenon? Trends in Plant Sciences, Vol. 11: pp. 492-498.

Osmont, K.S., N. Sadeghian, and M Freeling. 2006. Mosaic analysis of extended auricle1 (eta1) suggests that a two-way signaling pathway is involved in positioning the blade/sheath boundary in Zea mays. Developmental Biology, Vol. 295: pp. 1-12.

Williams, L.*, C.C. Carles*, K.S. Osmont*, and J.C. Fletcher. 2005. A database analysis method identifies an endogenous trans-acting short-interfering RNA that targets the Arabidopsis ARF2, ARF3, and ARF4 genes. PNAS, 102: 9703-9708. *-equal contributions

Osmont, K.S., L.A. Jesaitis, and M. Freeling. 2003. The extended auricle1 (eta1) gene is essential for the genetic network controlling post-initial maize leaf development. Genetics, 165: 1507-1519.