Diter von Wettstein

Poraet Diter af Katarine JPEG

R.A.Nilan Distinguished Professor







Curriculum Vitae (pdf)

Ph.D. Univ of Tübingen 1953
Ph.D. Univ of Stockholm 1953
D.Sc. Univ.of Stockholm 1957

My basic research interests have been and are in these areas:

  • Biosynthesis of the photosynthetic membrane and chloroplast biogenesis
  • Chromosome pairing, mechanism of crossing-over and genome analysis
  • Epigenetics designer Transcription Activator-Like Effectors

My research in plant breeding concern:

  • Development of proanthocyanidin-free barley (metabolic engineering)
  • Development of wheat compatible with celiac patients (Mutations by designer Transcription Activator-Like Effectors and Targeting Induced Local Lesions in Genomes)
  • Molecular genetics of stem rust and herbicide resistance in barley

Read more.

Yang, M.M., S.S. Wen, D.V. Mavrodi, O.V. Marodi, D. von Wettstein, L.S. Thomashow, J-H Guo, D.M. Weller (2014) Biological control of wheat root diseases by the CLP-producing strain Pseudomonas fluorescens HC1-07. Phytopathology 104,    3:248-256.

Rossig, C., C. Reinbothe, J. Gray, O. Valdes, D. von Wettstein, S. Reinbothe (2013) Three proteins mediate import of transit sequence-less precursors into the inner envelope of chloroplasts in Arabidopsis thaliana. Proc. Natl. Acad. Sci. U.S.A 110:19466-71.

Zhang, H., Y. Bian, X. Gou, Y. Dong, S. Rustgi, B. Zhang, C. Xu, N. Li, B. Qi, F. Han, D. von Wettstein, Bao Liu (2013) Intrinsic karyotype stability and gene copy number variations may have laid foundation for tetraploid wheat formation. Proc. Natl. Acad. Sci. U.S.A. 110:19466-71.

BrewAppiah, R.A., N. Ankrah, W. Liu, C.F. Konzak, D. von Wettstein, S. Rustgi (2013) Generation of doubled haploid transgenic wheat lines by microspore transformation. PloS One (2013) Nov 18;8 (11):e80155.                                            doi:10.1371/journal.pone.0080155.

Zhang, H., Y. Bian, X. Gou, B. Zhu, C. Xu, B. Qi, N. Li, S. Rustgi, H. Zhou, F. Han, J. Jiang, D. von Wettstein, B. Lui (2013) Persistent whole-chromosome aneuploidy is generally associated with nascent allohexaploid wheat. Proc. Natl. Acad. Sci., U.S.A. 110:3447-3452.

Wen, S., W.Nuan, P. Jinsong, G. Langen, A.T.R. Brew-Appiah, J. H. Mejias, C. Osorio, M. Yang, R. Gemini, C.P. Moehs, R.S. Zemetra, K.-H. Kogel, B.Liu, X. Wang, D. von Wettstein, S. Rustgi (2012) Structural genes of wheat and barley 5-methylcytosine DNA glycosylases and their potential applications for human health. Proc. Natl. Acad. Sci. U S A. 109, 20543-20548.

Mueller AH, C.Dockter, S.P. Gough, U. Lundqvist, D. von Wettstein, M. Hansson (2012) Characterization of mutations in barley fch2 encoding chlorophyllide a oxygenase. Plant Cell Physiol. 53(7):1232-46. doi: 10.1093/pcp/pcs062.

Ou, X, Y. Zhang, C. Xu,  X. Lin, Q. Zang, T.Zhuang, L. Jiang, D. von Wettstein,  B. Liu (2012) Transgenerational Inheritance of Modified DNA Methylation Patterns and Enhanced Tolerance Induced by Heavy Metal Stress in Rice (Oryza sativa L.). PLoS ONE 7(9): e41143. doi:10.1371/journal.pone.0041143.

Khatabi, B., A. Molitor, C. Lindermayr, S. Pfiffi, J. Durner, D. von Wettstein, K.-H. Kogel, P. Schäfer (2012) Ethylene supports colonization of plant roots by the mutualistic fungus Piriformospora indica. PLoS ONE 7: 4 e35502

Osorio, C., N.Wen, R.Gemini, R.Zemetra, D.von Wettstein, S.Rustgi (2012) Targeted modification of wheat grain protein to reduce the content of celiac causing epitopes. Funct. Integr. Genomics.12, 417-438.

Nirmala, J., T. Drader, P.K.Lawrence, C. Yin, S.Hulbert, C.M. Steber, B.J. Steffenson , L. J.  Szabo, D.von Wettstein, and A. Kleinhofs (2011) Concerted action of two avirulent spore effectors activates reaction to Puccinia graminis 1 (RPG1)-mediated cereal stem rust resistance. Proc. Natl. Acad. Sci. U S A. 108(35), 14676-14681.

Kou H.P., Y. Li,  X.X. Song, X.F. Ou, SC. Xing, J.Ma, D.von Wettstein and B.Liu (2011) Heritable alteration in DNA methylation induced by nitrogen-deficiency stress accompanies enhanced tolerance by progenies to the stress in rice (Oryza sativa L.). J. Plant Physiol. 168 (14), 1685-93. PMID: 21665325.

Zhang M., C. Xu, D. von Wettstein and B.Liu (2011) Tissue-Specific Differences in Cytosine Methylation and their Association with Differential Gene Expression in Sorghum bicolor. Plant Physiol. 156, 1955-1966.  PMID: 21632971.

Lee H., S. Rustgi, N.Kumar, I. Burke, J.P. Yenish, K.S. Gill, D.von Wettstein, and S.E. Ullrich (2011). Single nucleotide mutation in the barley acetohydroxy acid synthase (AHAS) gene confers resistance to imidazolinone herbicides. Proc. Natl. Acad. Sci. U S A. 108 (21), 8909-13. Epub 2011 May 5. PMID: 21551103.

Samol I, F. Buhr, A.Springer, S. Pollmann, A. Lahroussi, C.Rossig, D.von Wettstein, C. Reinbothe and S. Reinbothe (2011) Implication of the oep16-1 mutation in a flu-independent, singlet oxygen-regulated cell death pathway in Arabidopsis thaliana. Plant Cell Physiol. 52(1):84-95. PMID: 21098557.

Samol I, C. Rossig, F. Buhr, A.Springer, S.Pollmann, A.Lahroussi, D.von Wettstein, C. Reinbothe and S. Reinbothe (2011) The outer chloroplast envelope protein OEP16-1 for plastid import of NADPH:protochlorophyllide oxidoreductase A in Arabidopsis thaliana. Plant Cell Physiol. 2011 Jan;52(1):96-111. PMID: 21098556

Kogel, K.H.,  L.M. Voll, P. Schäfer, C. Jansen, Y. Wu, G. Langen, J. Imani, J. Hofmann, A. Schmiedl, S. Sonnewald, D. von Wettstein, R. J. Cook and U. Sonnewald (2010) Transcriptome and metabolome profiling of fieldgrown transgenic barley lack induced differences but show cultivar-specific variances. Proc. Natl. Acad. Sci. USA 107, 6198­-6203.

More publications (pdf)