Karen Sanguinet

Karen Sanguinet

Assistant Professor/Scientist

255 Johnson Hall
Department of Crop & Soil Sciences
PO Box 646420
Pullman WA 99164-6420 USA
Phone 509-335-3662


Google Scholar page


Ph.D.     University of California-Berkeley
Plant Biology, 2003

B.S.       University of Wisconsin-Madison
Horticulture with specialization in Vegetable Crops, 1998

B.S.        University of Wisconsin-Madison
Genetics with Honors, 1998


Curriculum Vitae

Research Experience

Assistant Professor, Iwate University, 2013-2014
Senior Research Fellow, University of Massachusetts-Amherst, 2009-2012
Marie Curie Postdoctoral Fellow, University of Lausanne, Switzerland, 2005-2009
Postdoctoral Researcher, Plant Gene Expression Center, Albany, CA, 2004-2005
Graduate Student Researcher, University of California-Berkeley, 1998-2003

Research Interest

Research themes in the Sanguinet lab focus on factors that modulate growth and development. We study the root architecture of the Pooideae subfamily of temperate grasses using developmental, genetic and genomics approaches. Through characterization and analysis of a suite of root mutants and natural accessions in Brachypodium distachyon, we hope to gain insight into the quantitative and qualitative control of homorhizic root architecture typical of the grasses. We are also interested in understanding the link between hormonal crosstalk and how the cell wall constrains morphogenesis.



(f/k/a Osmont, Karen S)

Cong, W., Y. Miao, L. Xu, Y. Zhang, C. Yuan, J. Wang, T. Zhuang, X. Lin, L. Jiang, N. Wang, J. Ma, K.A. Sanguinet, B. Liu, S. Rustgi, and X.0 Ou. Transgenerational memory of gene expression changes induced by heavy metal stress in rice (Oryza sativa L.) BMC Plant Biology, 19 (1), 282

Brew-Appiah, R.A.T., L.M. Peracchi, and K.A. Sanguinet. 2019. Never the two shall mix: Robust indel markers to ensure the fidelity of two pivotal and closely-related accessions of Brachypodium distachyon. Plants 8 (6), 153.

Ma, X., K.A. Sanguinet, and P. Jacoby. 2019. Performance of direct root-zone deficit irrigation on Vitis vinífera L. cv. ‘Cabernet Sauvignon’ production and water use efficiency in semi-arid southcentral Washington, Agricultural Water Management, 221, 47-57.

Zhang, Z., T. Fu, Z. Lui, X. Wang, H. Xun, G. Li, B. Ding, Y. Dong, X. Lin, K.A. Sanguinet, B. Liu, and Y. Wu. 2019. Extensive changes in gene expression and alternative splicing due to homeologous exchange in rice segmental allopolyploids, Theoretical and Applied Genetics, 1-14.

Clark, I., S.S. Jones, J.P. Reganold, K.A. Sanguinet, and K.M. Murphy. 2019. Agronomic performance of perennial grain genotypes in the Palouse region of the Pacific Northwest, USA, Frontiers in Sustainable Food Systems, 3, 39.

Lehman, T., and K.A. Sanguinet. 2019. Auxin and cell wall crosstalk as revealed by the Arabidopsis thaliana cellulose synthase mutant radially swollen 1, Plant and Cell Physiology, pcz055.

Brew-Appiah, R.A.T., and K.A. Sanguinet. 2018. Considerations of AOX functionality revealed by critical motifs and unique domains, International Journal of Molecular Sciences, 19(10), 2972

Brew-Appiah, R.A.T., Z.B. York, V. Krishnan, E. Roalson, and K.A. Sanguinet. 2018. Genome-wide identification and analysis of the ALTERNATIVE OXIDASE gene family in diploid and hexaploid wheat, PloS One 13 (8), e0201439

Handakumbura, P.P., K. Brow, I.P. Whitney, K. Zhao, K.A. Sanguinet, S.J. Lee, J. Olins, S.P. Romero-Gamboa, M.J. Harrington, C.J. Bascom, K. MacKinnon, M. Veling, L. Liu, J. Lee, J.P. Vogel, R.C. O’Malley, M. Bezanilla, L.E. Bartley, and S. Hazen. 2018. SECONDARY WALL ASSOCIATED MYB1 is a positive regulator of secondary cell wall thickening in Brachypodium distachyon and is not found in the Brassicaceae, The Plant Journal, 96 (3), 532-545

Wu, Y., Y. Sun, S. Sun, G. Li, J. Wang, B. Wang, X. Lin, M. Huang, Z. Gong, K.A. Sanguinet, Z. Zhang, and B. Liu. 2018. Aneuploidization under segmental allotetraploidy in rice and its phenotypic manifestation, Theoretical and Applied Genetics, 1-13

Martinez, S., A. Thompson, N. Wen, L. Murphey, K.A. Sanguinet, C. Steber, and K. Garland-Campbell. 2018. Registration of the Louise/Alpowa Wheat Recombinant Inbred Line Mapping Population, Journal of Plant Registrations doi:10.3198/jpr2017.08.0053crmp

Liu, D., N. Zefroosh, K. Hines, W. Fang, K.A. Sanguinet, L. Goldner, and T.I. Baskin. 2017. Cellulose synthase motility during primary cell wall synthesis in the grass Brachypodium distachyon, Scientific Reports, 7 (1): 15111

Lehman, T., A. Smertenko, and K.A. Sanguinet. 2017. Auxin, microtubules, and vesicular trafficking: conspirators behind the cell wall. Journal of Experimental Botany

Sun, S.,* Y. Wu*, X. Lin, J. Wang, J. Yu, Y. Sun, Y. Miao, Q. Li, K.A. Sanguinet, and B. Liu. 2017. Hybrid weakness in a rice interspecific hybrid is N-dependant, and accompanied by changes in gene expression at both total transcript level and parental allele partiitioning. PloS One 12 (3), e0172919. *co-first authors, co-corresponding authors

Itoh, J-I, Y. Sato, Y. Sato, K-I Hibara, S. Shimizu-Sato, H. Kobayashi, H. Takehisa, K.A. Sanguinet, N. Namiki, and Y. Nagamura. 2016. Genome-wide analysis of spatiotemporal gene expression patterns during early embryogenesis in rice. Development, 143: 1217-1227

Handakumbura, P.P., D.A. Matos, K.S. Osmont, M.J. Harrington, K. Heo, K. Kafle, S.H. Kim, T.I. Baskin, and S.P. Hazen. 2013. Perturbation of Brachypodium distachyon CELLULOSE SYNTHASE A4 or 7 results in abnormal cell walls. BMC Plant Biology, 13: 131.

Sankar, M., K.S. Osmont, J. Rolcik, B. Gujas, D. Tarkowska, M. Strnad, I. Xenarios, and C.S. Hardtke. 2011. A qualitative continuous model of cellular auxin and brassinosteroid signaling and their crosstalk. Bioinformatics, 27(10): 1404-1412.

Jun, J.H., E. Fiume, A. Roeder, L. Meng, V.K. Sharma, K.S Osmont, C. Baker, C.M. Ha, E.M. Meyerowitz, L.J. Feldman, and J.C. Fletcher. 2010. Comprehensive analysis of CLE gene expression and over-expression activity in Arabidopsis. Plant Physiology, 154: 1721-1736.

Scacchi, E.*, K.S. Osmont*, J. Beuchat, P. Salinas, M. Navarrete-Gómez, M. Trigueros, C. Ferrándiz, and C.S. Hardtke. 2009. Dynamic, auxin-responsive plasma membrane to nucleus movement of Arabidopsis BRX. Development, Vol. 136: pp. 2059-2067. *-equal contributions

Rodrigues, A., J. Santiago, S. Rubio, A. Saez, K.S. Osmont, J. Gadea, C.S. Hardtke, P.L. Rodriguez. 2009. The Short-Rooted Phenotype of the brevis radix Mutant Partly Reflects Root Abscisic Acid Hypersensitivity. Plant Physiology, 149: 1917-28.

Osmont, K.S. and C.S. Hardtke. 2008. The topless plant developmental phenotype explained! Genome Biology, 9:219.

Hardtke, C.S., E. Dorcey, K.S. Osmont, and R. Sibout. 2007. Phytohormone collaboration: zooming in on auxin-brassinosteroid interactions. Trends in Cell Biology, Vol. 17: pp. 485-492.

Osmont, K.S., R. Sibout, and C.S. Hardtke. 2007. Hidden Branches: Developments in Root System Architecture. Annual Review of Plant Biology, Vol. 58: pp. 93-113.

Mouchel, C.F., K.S. Osmont, and C.S. Hardtke. 2006. BRX mediates feedback between brassinosteroid levels and auxin signalling in root growth. Nature, Vol. 443: pp. 458-461.

Briggs, G.C., K.S. Osmont, C. Shindo, R. Sibout, and C.S. Hardtke. 2006. Unequal genetic redundancies in Arabidopsis – a neglected phenomenon? Trends in Plant Sciences, Vol. 11: pp. 492-498.

Osmont, K.S., N. Sadeghian, and M Freeling. 2006. Mosaic analysis of extended auricle1 (eta1) suggests that a two-way signaling pathway is involved in positioning the blade/sheath boundary in Zea mays. Developmental Biology, Vol. 295: pp. 1-12.

Williams, L.*, C.C. Carles*, K.S. Osmont*, and J.C. Fletcher. 2005. A database analysis method identifies an endogenous trans-acting short-interfering RNA that targets the Arabidopsis ARF2, ARF3, and ARF4 genes. PNAS, 102: 9703-9708. *-equal contributions

Osmont, K.S., L.A. Jesaitis, and M. Freeling. 2003. The extended auricle1 (eta1) gene is essential for the genetic network controlling post-initial maize leaf development. Genetics, 165: 1507-1519.